Research Article

Locally Advanced and Unresectable Cutaneous Squamous Cell Carcinoma: Outcomes of Concurrent Cetuximab and Radiotherapy

Table 2

Disease characteristics and treatment response.

PatientStage*RecurrentGross diseasePosttreatment response within the irradiated volumeMonths until PD (in or out of irradiated volume)

1T4N2bM0NoYesPR 6.4 (in)
2T0N2bM0YesYesCR14.7 (in), 16.3 (out)
3T0N2bM0R0YesNoN/A(Died with NED)
4T4N0M0YesYesSD(Died without PD)
5T0N1M0YesYesCR(Alive with NED)
6T4N0M0YesYesSD(Alive with NED)
7T2N2bM0NoYesPD (during treatment)1.7 (in and out)
8T0N2bM1YesYesCR2.1 (out), 5.0 (in)
9T2N2bM0YesYesCR4.4 (out)
10T4N0M0YesYesSD52.2 (in)
11T0N3M1YesYesPR1.6 (out)
12T4N0M0NoYesPR4.4 (out), 4.7 (in)

Disease status at the start of therapy and investigator assessed response 4–12 weeks after therapy are presented.
All patients were staged clinically, except patient 3, who was staged pathologically.
PR: partial response, CR: complete response, SD: stable disease, PD: progressive disease, NED: no evidence of disease, IV: irradiated volume, and N/A: not applicable (because patient received adjuvant therapy no measureable disease for response assessment ).