Cutaneous Human Papillomavirus Infection and Development of Subsequent Squamous Cell Carcinoma of the Skin

Table 2

Associations between baseline skin cancer risk factors and subsequent cutaneous squamous cell carcinoma (SCC).

Variable	No subsequent SCC (); (%)	Subsequent SCC (); (%)	value for Chi Square test
Age [mean (STD)]	62.9 (12.4)	65.4 (8.4)
Gender
Female	24 (40.7)	26 (28.6)	0.12
Male	35 (59.3)	65 (71.4)
History of blistering sunburn prior to index SCC diagnosis
No	15 (28.3)	14 (18.2)
Yes	38 (71.7)	63 (81.8)	0.17
Tanning ability
No	11 (21.6)	12 (15.0)
Yes	40 (78.4)	68 (85.0)	0.33
Job in sun for more than 3 months at any time in life prior to the index SCC diagnosis
No	31 (59.6)	39 (48.7)	0.22
Yes	21 (40.4)	41 (51.2)
Smoking
Never	17 (32.1)	23 (29.9)
Ever	36 (67.9)	54 (70.1)	0.79
Alcohol
Never drinker	12 (23.5)	15 (18.7)	0.51
1 or more drinks in past 1 year	39 (76.5)	65 (81.2)
History of SCC prior to index SCC diagnosis
No	7 (15.6)	1 (1.5)
Yes	38 (84.4)	65 (98.5)
History of BCC prior to index SCC diagnosis
No	7 (21.2)	2 (3.6)
Yes	26 (78.8)	53 (96.4)
History of SCC and BCC prior to index SCC diagnosis
No	7 (21.9)	1 (2.0)
Yes	25 (78.1)	49 (98.0)
Number of HPV types in index SCC tumors
0	23 (42.6)	22 (28.6)	0.17
1	12 (22.2)	14 (18.2)
2–5	17 (31.5)	33 (42.9)
>5	2 (3.7)	8 (10.4)

¹Student’s -test. ²Fisher’s exact test.