Microvessel Density in Patients with Cutaneous Melanoma: An Up-to-Date Systematic Review and Meta-Analysis

Table 4

Clark’s level and Breslow thickness.

Author	Clark’s level						Breslow thickness
	0	1	2	3	4	5	1	2	3	4	5
Döme et al.	n/a	n/a	n/a	n/a	n/a	n/a	13 (28.9%), <1.5 mm		32 (71.11%), >1.5 mm
Hillen et al.	n/a	n/a	n/a	n/a	n/a	n/a	14 (24.1%)	23 (39.7%)	12 (20.7%) 1.51–3 mm		9 (15.5%)
Ilmonen et al.	1 (1.2%)		3 (3.57%)	51 (60.71%)	25 (29.76%)	4 (4.76%)	24 (28.57%)	25 (29.76%)	34 (40,47%), >1.5 mm
Massi et al.	0 (0%)	0 (0%)	0 (0%)	4 (8.8%)	40 (88.8%)	1 (2.2%)	Cases: 4.3 (1.23) mm Controls: n/a	0 (0%)	0 (0%)	0 (0%)	4 (8.8%)
Pastushenko et al.	n/a	n/a	n/a	n/a	n/a	n/a	58 (30.05%) ≤ 1 mm, 39 (19.89%) 1-2 mm, 44 (22.44%) 2–4 mm, 57 (29.08%) > 4 mm
Ribatti et al.	n/a	n/a	n/a	n/a	n/a	n/a	0 (0%), ≤1.5 m		25 (100%), >1.5 mm
Shimizu et al.	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Straume et al.	n/a	n/a	n/a	84	97	100	n/a	n/a	n/a	n/a	n/a
Valencak et al.	6 (5%)	1 (0.833%)	14 (11.667%)	45 (37.5%)	51 (42.5%)	3 (2.5%)	n/a	n/a	n/a	n/a	n/a