Comparison of the Effect of Alpha and Hydrocortisone Ointments on Prevention of Acute Skin Complications Due to Radiotherapy in Breast Cancer Patients

Table 4

Comparing two groups in terms of skin complication, pain and burning, and skin itching in various times.

Complication		Severity	Hydrocortisone	Alpha	Total	value
Skin complication	W2	G1	1 (2.3)	0	1 (1.2)	0.314
	W3	G1	6 (14.0)	3 (7.0)	9 (10.5)	0.33
		G2	1 (2.3)	0	1 (1.2)
	Total		7 (16.3)	3 (7.0)	10 (11.7)
	W4	G1	15 (34.9)	5 (11.6)	20 (23.3)	0.001
		G2	5 (11.6)	0	5 (5.8)
	Total		20 (46.5)	5 (11.6)	25 (29.1)
	W5	G1	27 (62.8)	17 (39.5)	44 (51.1)	<0.001
		G2	9 (20.9)	0	9 (10.5)
	Total		36 (83.7)	17 (39.5)	53 (61.6)
	W6	G1	14 (32.6)	6 (14.0)	20 (23.3)	<0.001
		G2	8 (18.6)	0	8 (9.3)
	Total		22 (51.2)	6 (14.0)	28 (32.6)
Pain and burning	W2	Mild	2 (4.7)	1 (2.3)	3 (3.5)	0.557
	W3	Mild	9 (20.9)	6 (14.0)	15 (17.4)	0.394
	W4	Mild	29 (67.4)	8 (18.6)	37 (43.0)	<0.001
	W5	Mild	33 (76.7)	18 (41.9)	51 (59.3)	0.001
		Moderate	1 (2.3)	0	1 (1.2)
	W6	Mild	1 (2.3)	0	1 (1.2)	0.314
Skin itching	W2	Mild	1 (2.3)	0	1 (1.2)	0.314
	W3	Mild	4 (9.3)	12 (27.9)	16 (18.6)	0.027
	W4	Mild	5 (11.6)	15 (34.9)	20 (23.3)	0.001
		Moderate	0	5 (11.6)	5 (5.8)
	W5	Mild	14 (32.6)	14 (32.6)	28 (32.6)	1.0
	W6	Mild	3 (7.0)	0	3 (3.5)	0.078

W = week, G = grade.