Interest and Utility of MC1R Testing for Melanoma Risk in Dermatology Patients with a History of Nonmelanoma Skin Cancer
Table 1
Participant baseline characteristics, overall, and saliva sample return status.
Characteristic
Group
All (n = 50)
Noncompleters (n = 29)
Completers (n = 21)
-value
DEMOGRAPHICS
Gender
Female
28 (56%)
14 (48%)
14 (67%)
0.20
Education
No college degree
9 (18%)
6 (21%)
3 (14%)
0.74
College graduate
18 (36%)
8 (28%)
10 (48%)
Graduate degree
23 (46%)
15 (52%)
8 (38%)
Age (years)
Mean (SD) [35–78]
63.6 (10.7)
62.9 (10.8)
64.6 (10.8)
0.11
Born outside US
Yes
8 (16%)
6 (21%)
2 (10%)
0.29
Marital Status (n = 49)
Single
6 (12%)
4 (14%)
2 (10%)
0.51
Married/Cohabitating
39 (80%)
23 (82%)
16 (76%)
Divorced/Separated
3 (6%)
1 (4%)
2 (10%)
Widowed
1 (2%)
0 (0%)
1 (5%)
Employed
Yes
26 (52%)
18 (62%)
8 (38%)
0.09
SKIN CANCER RISK FACTORS
Other Cancer
Yes
16 (32%)
8 (28%)
8 (38%)
0.43
Family History (n = 48)
Yes
31 (65%)
17 (61%)
14 (70%)
0.51
Burnability (n = 48)
Severe
1 (2%)
0 (0%)
1 (5%)
0.13
Painful/peeling
20 (42%)
10 (36%)
10 (50%)
Mild/tan
27 (56%)
18 (64%)
9 (45%)
Tannability (n = 45)
Very brown & tanned
6 (13%)
3 (12%)
3 (15%)
0.26
Moderately tanned
13 (29%)
10 (40%)
3 (15%)
Mild tan/some peeling
16 (36%)
8 (32%)
8 (40%)
Freckle/no tan
10 (22%)
4 (16%)
6 (30%)
Lifetime number of sunburns (n = 48)
0
10 (21%)
7 (25%)
3 (15%)
0.48
1–2
14 (29%)
9 (32%)
5 (25%)
3–5
11 (23%)
5 (18%)
6 (30%)
6–9
6 (13%)
3 (11%)
3 (15%)
10–14
4 (8%)
2 (7%)
2 (10%)
15–19
1 (2%)
1 (4%)
0 (0%)
20 or more
2 (4%)
1 (4%)
1 (5%)
PSYCHOSOCIAL
Perceived risk (absolute)
Unlikely to get SC
4 (8%)
3 (10%)
1 (5%)
0.67
Likely to get SC
40 (80%)
22 (76%)
18 (86%)
No idea
6 (12%)
4 (14%)
2 (10%)
Perceived risk (absolute)
1 No chance
3 (6%)
1 (3%)
2 (10%)
0.29
2 Very Unlikely
1 (2%)
1 (3%)
0 (0%)
3 Unlikely
3 (6%)
3 (10%)
0 (0%)
4 Moderate Chance
13 (26%)
9 (31%)
4 (19%)
5 Likely
17 (34%)
11 (38%)
6 (29%)
6 Very Likely
12 (24%)
4 (14%)
8 (38%)
7 Certain to happen
1 (2%)
0 (0%)
1 (5%)
Perc. risk (abs.)
Mean (SD) [1–7]
4.60 (1.36)
4.38 (1.18)
4.90 (1.55)
0.18
Perceived risk (comparative) (n = 49)
1 Well below average
0 (0%)
0 (0%)
0 (0%)
0.11
2 Below average
2 (4%)
2 (7%)
0 (0%)
3 Average
16 (33%)
10 (36%)
6 (29%)
4 Above average
27 (55%)
15 (54%)
12 (57%)
5 Well above average
4 (8%)
1 (4%)
3 (14%)
Perc. risk (comp.)
Mean (SD) [1–5]
3.67 (0.69)
3.54 (0.69)
3.86 (0.65)
0.11
Worry about SC
1 Rarely or never
28 (56%)
17 (59%)
11 (52%)
0.81
2 Sometimes
11 (22%)
5 (17%)
6 (29%)
3 Often
10 (20%)
7 (24%)
3 (14%)
4 All the time
1 (2%)
0 (0%)
1 (5%)
Worry about SC
Mean (SD) [1–4]
1.68 (0.87)
1.66 (0.86)
1.71 (0.90)
0.81
Concern about SC
1 Not at all concerned
24 (48%)
15 (52%)
9 (43%)
0.84
2
10 (20%)
4 (14%)
6 (29%)
3
11 (22%)
6 (21%)
5 (24%)
4 Very concerned
5 (10%)
4 (14%)
1 (5%)
Concern about SC
Mean (SD) [1–4]
1.94 (1.06)
1.97 (1.15)
1.90 (0.94)
0.84
Importance of learning about your genes
1 Not at all important
2 (4%)
0 (0%)
2 (10%)
0.25
2
1 (2%)
0 (0%)
1 (5%)
3
0 (0%)
0 (0%)
0 (0%)
4 Neither unimportant nor important
4 (8%)
3 (10%)
1 (5%)
5
5 (10%)
4 (14%)
1 (5%)
6
8 (16%)
4 (14%)
4 (19%)
7 Very important
30 (60%)
18 (62%)
12 (57%)
Importance
Mean (SD) [1–7]
6.06 (1.54)
6.28 (1.07)
5.76 (2.02)
0.25
INFORMATION SEEKING
SC
Yes
44 (88%)
26 (90%)
18 (86%)
0.67
Genetic testing
Yes
13 (26%)
9 (31%)
4 (19%)
0.34
Note that -values for continuous variables (e.g., age) are based on independent samples t-tests; purely categorical variables (e.g., gender and marital status) are based on the Chi-square test; and ordinal variables (e.g., education or number of lifetime sunburns) are based on Mantel-Haenszel Chi-square test. SC denotes skin cancer. “Noncompleters” includes the 29 participants who either did not log on to the study website (n = 26), logged on and did not register a decision to test (n = 2) or requested a kit but did not return it (n = 1).
