Journal of Sports Medicine / 2018 / Article / Tab 6

Review Article

Interactions of Gut Microbiota, Endotoxemia, Immune Function, and Diet in Exertional Heatstroke

Table 6

Clinical and laboratory results, which are observed in advanced cases of exertional heatstroke and exemplify multiple organ dysfunction or failure.

Signs and symptomsLaboratory/autopsy findings

(i)  Internal body temperature > 40°C 
(ii) Hyperventilation  
(iii) Headache 
(iv) Central nervous system involvement (loss of mental acuity, fatigue, weakness, confusion, dizziness, delirium, loss of coordination) 
(v) Hypotension 
(vi) Tachycardia 
(vii) Circulatory shock 
(viii) Liver failure 
(ix) Kidney failure 
(x) Nausea, vomiting 
(xi) Diarrhea
(i)  Intestinal ischemia 
(ii) Metabolic acidosis with respiratory alkalosis 
(iii) Elevated plasma lactate 
(iv) Elevated plasma LPS 
(v) Elevated plasma cytokines 
(vi) Elevated hematocrit 
(vii) Elevated liver enzymes (ALT, AST) in plasma 
(viii) Disseminated intravascular coagulation 
(ix) Leukocytosis 
(x) Neutropenia 
(xi) Tissue hemorrhage with necrosis 
(xii) Intestinal lesions

Sources. [43, 44, 119, 120].

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