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Spectroscopy
Volume 18, Issue 2, Pages 355-362
http://dx.doi.org/10.1155/2004/949018

The fragmentation pathways of azaspiracids elucidated using positive nanospray hybrid quadrupole time-of-flight (QqTOF) mass spectrometry

Brett Hamilton, Mónica Díaz Sierra, Mary Lehane, Ambrose Furey, and Kevin J. James

PROTEOBIO, Mass Spectrometry Centre for Proteomics and Biotoxin Research, Department of Chemistry, Cork Institute of Technology, Cork, Ireland

Copyright © 2004 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [12 citations]

The following is the list of published articles that have cited the current article.

  • James, Fidalgo Sáez, Furey, and Lehane, “Azaspiracid poisoning, the food-borne illness associated with shellfish consumption,” Food Additives and Contaminants, vol. 21, no. 9, pp. 879–892, 2004. View at Publisher · View at Google Scholar
  • Kj James, Mjf Saez, A Furey, and M Lehane, “Azaspiracid poisoning, the food-borne illness associated with shellfish consumption,” Food Additives and Contaminants, vol. 21, no. 9, pp. 879–892, 2004. View at Publisher · View at Google Scholar
  • Craig J. Forsyth, Jianyan Xu, Son T. Nguyen, Ingunn A. Samdal, Lyn R. Briggs, Thomas Rundberget, Morten Sandvik, and Christopher O. Miles, “Antibodies with broad specificity to azaspiracids by use of synthetic haptens,” Journal of the American Chemical Society, vol. 128, no. 47, pp. 15114–15116, 2006. View at Publisher · View at Google Scholar
  • Michael O. Frederick, Sandra De Lamo Marin, Kim D. Janda, Nicolaou, and Tobin J. Dickerson, “Monoclonal antibodies with orthogonal azaspiracid epitopes,” ChemBioChem, vol. 10, no. 10, pp. 1625–1629, 2009. View at Publisher · View at Google Scholar
  • Michael G. Cahill, Giovanni Caprioli, Sauro Vittori, and Kevin J. James, “Elucidation of the mass fragmentation pathways of potato glycoalkaloids and aglycons using Orbitrap mass spectrometry,” Journal of Mass Spectrometry, vol. 45, no. 9, pp. 1019–1025, 2010. View at Publisher · View at Google Scholar
  • Ambrose Furey, Sinead O'Doherty, Keith O'Callaghan, Mary Lehane, and Kevin J. James, “Azaspiracid poisoning (AZP) toxins in shellfish: Toxicological and health considerations,” Toxicon, vol. 56, no. 2, pp. 173–190, 2010. View at Publisher · View at Google Scholar
  • Isa Ruppen Canás, Keith O'Callaghan, Cian Moroney, Brett Hamilton, Kevin J. James, and Ambrose Furey, “The development of a rapid method for the isolation of four azaspiracids for use as reference materials for quantitative LC-MS-MS methods,” Analytical and Bioanalytical Chemistry, vol. 398, no. 3, pp. 1477–1491, 2010. View at Publisher · View at Google Scholar
  • Zuzana Skrabakova, John O'Halloran, Frank N. A. M. van Pelt, and Kevin J. James, “Food contaminant analysis at ultra-high mass resolution: application of hybrid linear ion trap - orbitrap mass spectrometry for the determination of the polyether toxins, azaspiracids, in shellfish,” Rapid Communications in Mass Spectrometry, vol. 24, no. 20, pp. 2966–2974, 2010. View at Publisher · View at Google Scholar
  • Daniel O'Driscoll, Zuzana Škrabáková, John O'Halloran, Frank N. A. M. Van Pelt, and Kevin J. James, “Mussels increase xenobiotic (azaspiracid) toxicity using a unique bioconversion mechanism,” Environmental Science and Technology, vol. 45, no. 7, pp. 3102–3108, 2011. View at Publisher · View at Google Scholar
  • Bébhine Carey, Maria José Fidalgo Sáez, Brett Hamilton, John O'Halloran, Frank N. A. M. Pelt, and Kevin J. James, “Elucidation of the mass fragmentation pathways of the polyether marine toxins, dinophysistoxins, and identification of isomer discrimination processes,” Rapid Communications in Mass Spectrometry, vol. 26, no. 16, pp. 1793–1802, 2012. View at Publisher · View at Google Scholar
  • Daniel O’Driscoll, Zuzana Škrabáková, and Kevin J. James, “Confirmation of Extensive Natural Distribution of Azaspiracids in the Tissue Compartments of Mussels (Mytilus edulis),” Toxicon, 2014. View at Publisher · View at Google Scholar
  • Rachele Rossi, Carmela Dell’Aversano, Bernd Krock, Adriana Zingone, Patrizia Ciminiello, Isabella Percopo, Urban Tillmann, and Vittorio Soprano, “Mediterranean Azadinium dexteroporum (Dinophyceae) produces six novel azaspiracids and azaspiracid-35: a structural study by a multi-platform mass spectrometry approach,” Analytical and Bioanalytical Chemistry, vol. 409, no. 4, pp. 1121–1134, 2017. View at Publisher · View at Google Scholar