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Spectroscopy
Volume 20, Issue 4, Pages 177-183
http://dx.doi.org/10.1155/2006/857517

The effective correlation time τ in jaw cysts determined from 400 MHz NMR T1 and T2 measurements

Hatice Budak,1 M. Zafer Köylü,1 and U. Nezih Yilmaz2

1Department of Physics, Faculty of Science, University of Dicle, 21280 Diyarbakır, Turkey
2Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University of Dicle, 21280 Diyarbakır, Turkey

Copyright © 2006 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Macromolecular crowding is a general phenomenon of biological systems, and the evaluation of a correlation time for a specific molecule is difficult when the molecular crowding exists. The determination of an effective correlation time may therefore give useful insights into molecular dynamics of such systems. In this work, the relaxation rates in the mixture of D2O (80%) and cystic fluid (20%) were measured with a NMR operating at 400 MHz for three types of cysts (non-infected radicular, infected radicular and hemorrhagic). The effective correlation times (τ values) were then determined by using a formula derived from the observed relaxation rates. The τ value of the infected cyst was found to be longer than those of the others for the studied cases. The present data suggest that an effective correlation time for fluids with macromolecular crowding can be determined from NMR relaxation measurements.