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Spectroscopy
Volume 22, Issue 1, Pages 51-56
http://dx.doi.org/10.3233/SPE-2008-0328

Preparation, spectral characterization and antibacterial studies of silver(I) complexes of 2-mercaptopyridine and thiomalate

Muhammad Hanif,1 Aisha Saddiqa,1 Shahida Hasnain,2 Saeed Ahmad,1,5 Ghulam Rabbani,1 and Anvarhusein A. Isab3,4

1Department of Chemistry, University of Engineering and Technology, Lahore, Pakistan
2Department of Microbiology and Molecular Genetics, Punjab University, Lahore, Pakistan
3Department of Chemistry, King Fahd University of Petroleum and Minerals, Dhahran, Saudi Arabia
4Department of Chemistry, King Fahd University of Petroleum and Minerals, Dhahran-31261, Saudi Arabia
5Department of Chemistry, University of Engineering and Technology, Lahore-54890, Pakistan

Copyright © 2008 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Silver(I) complexes of 2-mercaptopyridine (Mpy), [Ag(Mpy)]NO3 and [Ag(Mpy)2]NO3, and the first mixed-ligand complex having a thione and thiolate coordinated to Ag(I), [Mpy–Ag–Tm] (Tm═thiomalate) have been prepared and characterized by IR and NMR spectroscopy. The 1H and 13C NMR spectra show the presence of both ligands in the mixed-ligand complex, [Mpy–Ag–Tm]. An upfield shift is observed in the >C═S resonance of Mpy and C═O resonances of thiomalate in 13C NMR, while the other resonances are shifted downfield. The complexes showed relatively high antibacterial activity (inhibition zone of 6–11 mm) against a gram +ve bacterium, Bacillus subtilis, as compared to that (inhibition zone of 4 mm) against a gram –ve bacterium, Escherichia coli.