Journal of Spectroscopy

Journal of Spectroscopy / 2008 / Article

Open Access

Volume 22 |Article ID 294547 | https://doi.org/10.3233/SPE-2008-0366

João Carlos Lázaro, Carlos J. de Lima, Leonardo M. Moreira, Landulfo Silveira Jr., Nelson J. F. da Silveira, Antonio Balbin Villaverde, Marcos Tadeu T. Pacheco, "Analysis of the alteration in the optical configuration of Raman spectrometer: Optimization of signal-to-noise ratio (SNR) in a specific wavelength range of clinical interest", Journal of Spectroscopy, vol. 22, Article ID 294547, 8 pages, 2008. https://doi.org/10.3233/SPE-2008-0366

Analysis of the alteration in the optical configuration of Raman spectrometer: Optimization of signal-to-noise ratio (SNR) in a specific wavelength range of clinical interest

Abstract

The present article is focused on the optimization of the optical parameters of a Raman spectrometer in order to obtain a minimum width of its spectral lines. In this way, using as reference the width of a fingerprint band of a calcified biological tissue, a spectral line without distortion or any loss of resolution was identified. This optimization is employed with the aim of improvement of the signal-to-noise ratio (SNR). A great improvement in the efficiency of the spectral collect was obtained, which can reduce significantly the time of diagnosis of target tissues, such as the calcified coronarian tissue. Therefore, the potential application of this new spectroscopic system increases the efficiency and precision, favoring the security of this technique to future in vivo applications. The excellent results obtained in this work become this spectroscopic system a powerful tool to the clinical diagnosis of several diseases.

Copyright © 2008 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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