Ghulam Rabbani, Anvarhusein A. Isab, Abdul Rahman Al-Arfaj, Saeed Ahmad, Muhammad Saleem, Abdul Hameed, Erum Akbar, "Synthesis, spectroscopic characterization and antimicrobial studies of mercury(II) complexes of thiolates", Journal of Spectroscopy, vol. 23, Article ID 406563, 6 pages, 2009. https://doi.org/10.3233/SPE-2009-0369
Synthesis, spectroscopic characterization and antimicrobial studies of mercury(II) complexes of thiolates
Mercury(II) complexes of thiolates having the general formula [Hg(RS)Cl2]− and [Hg(RS)2] have been prepared and characterized by IR and NMR (1H and 13C) spectroscopy (RSH = 2-aminoethanethiol hydrochloride (Aet), cysteine (Cys), thiosalicylic acid (Ts) and 2-mercaptonicotinic acid (Mnt)). The spectral data suggests that the coordination of thiolates to mercury(II) occurs through the sulfur as indicated by the absence of S–H vibrations in IR and significant downfield shifts in the C–S resonance in 13C NMR. However, in Mnt complexes, coordination through both sulfur and nitrogen is indicated. Antimicrobial activities of the complexes were evaluated by minimum inhibitory concentration and the results showed that the complexes exhibited a wide range of activities against gram-negative bacteria (E. coli, P. aeruginosa), while moderate activity was observed against a mold, P. citrinum.
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