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Spectroscopy
Volume 23, Issue 1, Pages 45-50
http://dx.doi.org/10.3233/SPE-2009-0369

Synthesis, spectroscopic characterization and antimicrobial studies of mercury(II) complexes of thiolates

Ghulam Rabbani,1 Anvarhusein A. Isab,2,4 Abdul Rahman Al-Arfaj,2 Saeed Ahmad,1 Muhammad Saleem,3 Abdul Hameed,3 and Erum Akbar1

1Department of Chemistry, University of Engineering and Technology, Lahore, Pakistan
2Department of Chemistry, King Fahd University of Petroleum and Minerals, Dhahran, Saudi Arabia
3PAEC, Islamabad GPO, Pakistan
4Department of Chemistry, King Fahd University of Petroleum and Minerals, Dhahran 31261, Saudi Arabia

Copyright © 2009 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Mercury(II) complexes of thiolates having the general formula [Hg(RS)Cl2] and [Hg(RS)2] have been prepared and characterized by IR and NMR (1H and 13C) spectroscopy (RSH = 2-aminoethanethiol hydrochloride (Aet), cysteine (Cys), thiosalicylic acid (Ts) and 2-mercaptonicotinic acid (Mnt)). The spectral data suggests that the coordination of thiolates to mercury(II) occurs through the sulfur as indicated by the absence of S–H vibrations in IR and significant downfield shifts in the C–S resonance in 13C NMR. However, in Mnt complexes, coordination through both sulfur and nitrogen is indicated. Antimicrobial activities of the complexes were evaluated by minimum inhibitory concentration and the results showed that the complexes exhibited a wide range of activities against gram-negative bacteria (E. coli, P. aeruginosa), while moderate activity was observed against a mold, P. citrinum.