From Molecule to Tissue: XIII European Conference on the Spectroscopy of Biological Molecules, Palermo, Italy, August 28–September 2, 2009, Part 1 of 2View this Special Issue
Ohki Kambara, Keisuke Tominaga, "Structural fluctuation of proteins revealed by terahertz time-domain spectroscopy", Journal of Spectroscopy, vol. 24, Article ID 391586, 4 pages, 2010. https://doi.org/10.3233/SPE-2010-0422
Structural fluctuation of proteins revealed by terahertz time-domain spectroscopy
We have measured spectra of the absorption coefficient and refractive index of hen egg white lysozyme in the wavenumber region from 7 cm–1 to 50 cm–1 by terahertz (THz) time-domain spectroscopy. From comparison with the results of the inelastic neutron scattering experiment it is concluded that analysis of the THz spectra provides information on the vibrational density of states. We studied temperature dependence of the THz spectra as well as hydration effect on them to discuss structural fluctuation of the protein. We observed dynamical transition at around 210 K for lysozyme.
Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.