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Spectroscopy
Volume 24, Issue 6, Pages 593-599
http://dx.doi.org/10.3233/SPE-2010-0489

Biomedical application of Mössbauer spectroscopy with a high velocity resolution: Revealing of small variations

M. I. Oshtrakh,1 V. A. Semionkin,1,2 O. B. Milder,1,3 I. V. Alenkina,1,2 and E. G. Novikov1,2

1Faculty of Physical Techniques and Devices for Quality Control, Physical–Technical Department, Ural Federal University, Ekaterinburg, Russian Federation
2Faculty of Experimental Physics, Physical–Technical Department, Ural Federal University, Ekaterinburg, Russian Federation
3Radio–Technical Department, Ural Federal University, Ekaterinburg, Russian Federation

Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Application of Mössbauer spectroscopy with a high velocity resolution for study different hemoglobins, ferritin, its models and chicken liver and spleen as well as normal and lymphoid chicken spleen demonstrated revealing of small variations of hyperfine parameters related to small variations of iron stereochemistry in biomolecules. These data demonstrate that Mössbauer spectroscopy with a high velocity resolution may be useful in biomedical research to distinguish small variations of iron-containing proteins in normal and pathological cases.