Quantitative Evaluation of Acetaminophen in Oral Solutions by Dispersive Raman Spectroscopy for Quality Control

Table 3

Solutions of different concentrations (160, 200, and 240 mg/mL) used to calculate the precision (RSD) and accuracy (AC).

Real concentration (mg/mL)VO
RS/PLS (mg/mL)
DAC (mg/mL)SD (mg/mL)RSD (%)AD (mg/mL)RD (%)AC (%)

160168.5167.71.00.6−7.7−4.6104,8
166.8
168.1
167.1
169.2
166.7

200194.9197.82.91.5−2.2−1.199.0
198.2
198.2
195.6
196.4
203.1

240 223.6224.8
230.1**
13.4
4.0**
6.0
1.7**
−9.9**−4.3**98.5
232.5
233.2
*198.5
228.9
232.3

Outlier, recalculated values after outlier being excluded.