Can Biofluids Metabolic Profiling Help to Improve Healthcare during Pregnancy?
Table 2
Summary of the impact of disorders on the metabolite profiling of 2nd trimester amniotic fluid, urine, and blood plasma.
Disorder
FM
Prediagnostic GDM
Pre-PTD
Pre-PROM
Chromosomal disorders
Biofluid
Amniotic fluid
+++
++
+
+
+
Maternal blood plasma
+++*
+
a
b
+**
Maternal urine
+++
++
+
b
++**
aInsufficient sample numbers at this stage, bno metabolite changes noted, *different malformation types, and **chromosomal disorders are apparently distinguishable, + small impact, ++ medium impact, +++ large impact.