Synchrotron FTIR Microspectroscopy Study of the Striatum in 6-Hydroxydopamine Rat Model of Parkinson's Disease

Table 3

The percentage compositions of protein secondary structure in the striatal neurons.

Secondary structureControlPD lesioned sidePD unlesioned side

β-sheet 2 8 . 8 ± 1 . 6 % 4 6 . 2 ± 0 . 8 9 %** ( 𝑃 = 0 . 0 0 1 ) 3 9 . 4 ± 0 . 8 1 %** ( 𝑃 = 0 . 0 0 1 )
α-helix 2 8 . 5 ± 1 . 5 % 2 6 ± 0 . 5 1 % ( 𝑃 = 0 . 0 0 4 ) 2 5 . 2 ± 0 . 6 1 % ** ( 𝑃 = 0 . 0 0 4 )
Unordered structure 4 2 . 6 ± 1 . 8 % 2 7 . 8 ± 0 . 7 6 %** ( 𝑃 = 0 . 0 0 1 ) 3 5 . 3 ± 0 . 8 1 %** ( 𝑃 = 0 . 0 0 1 )

**Statistically significant differences between control and PD group were marked, the 𝑃 values of Mann-Whitney 𝑈 test were shown in the parenthesis.