Spectrophotometric Determination of Thioridazine Hydrochloride in Tablets and Biological Fluids by Ion-Pair and Oxidation Reactions
Table 2
Evaluation of intraday and interday accuracy and precision of the proposed methods.
| Method | THZ taken μg/mL | Intraday | Interday | THZ founda, μg/mL | REb, % | RSD, % | THZ found, μg/mL | RE, % | RSD, % |
| BCG | 8 | 7.999 | −0.002 | 1.653 | 7.999 | −0.002 | 2.025 | 16 | 15.999 | −0.004 | 0.796 | 15.999 | −0.004 | 1.259 | 24 | 23.999 | −0.002 | 0.421 | 23.999 | −0.002 | 1.165 |
| BCP | 8 | 7.9996 | −0.004 | 0.853 | 7.9996 | −0.002 | 2.174 | 16 | 15.999 | −0.006 | 1.312 | 15.999 | −0.006 | 1.774 | 24 | 23.999 | −0.002 | 0.728 | 23.999 | −0.002 | 1.927 |
| KMnO4 + IC | 0.8 | 0.801 | 0.026 | 1.236 | 0.799 | −4 × 10−3 | 0.929 | 1.6 | 1.599 | −4 × 10−3 | 1.052 | 1.599 | −2 × 10−3 | 0.974 | 2.4 | 2.399 | −2 × 10−3 | 0.717 | 2.399 | −2 × 10−3 | 0.424 |
| KMnO4 + MO | 0.4 | 0.399 | −4 × 10−3 | 1.648 | 3.999 | −4 × 10−3 | 1.355 | 0.8 | 0.799 | −2 × 10−3 | 1.807 | 0.799 | −2 × 10−3 | 1.889 | 1.6 | 1.599 | −2 × 10−3 | 1.660 | 1.599 | −4 × 10−3 | 0.803 |
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aMean value of five determinations.
bRE: relative error.
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