Spectrophotometric Determination of Thioridazine Hydrochloride in Tablets and Biological Fluids by Ion-Pair and Oxidation Reactions

Table 2

Evaluation of intraday and interday accuracy and precision of the proposed methods.

MethodTHZ taken μg/mLIntradayInterday
THZ founda, μg/mLREb, %RSD, %THZ found, μg/mLRE, %RSD, %

BCG87.999−0.0021.6537.999−0.0022.025
1615.999−0.0040.79615.999−0.0041.259
2423.999−0.0020.42123.999−0.0021.165

BCP87.9996−0.0040.8537.9996−0.0022.174
1615.999−0.0061.31215.999−0.0061.774
2423.999−0.0020.72823.999−0.0021.927

KMnO4 + IC0.80.8010.0261.2360.799−4 × 10−30.929
1.61.599−4 × 10−31.0521.599−2 × 10−30.974
2.42.399−2 × 10−30.7172.399−2 × 10−30.424

KMnO4 + MO0.40.399−4 × 10−31.6483.999−4 × 10−31.355
0.80.799−2 × 10−31.8070.799−2 × 10−31.889
1.61.599−2 × 10−31.6601.599−4 × 10−30.803

aMean value of five determinations.
bRE: relative error.