Spectrophotometric Studies on the Thermodynamics of the ds-DNA Interaction with Irinotecan for a Better Understanding of Anticancer Drug-DNA Interactions

Table 3

The effect of salt concentration (KCl) on free energy changes (Δ𝐺⁰, Δ𝐺⁰_𝑝𝑒 and Δ𝐺⁰_𝑡).

[K^+] (mol L^−1)	Δ𝐺^0 (KJ mol^−1)	Δ𝐺^0𝑝𝑒 (kJ mol^−1)	Δ𝐺^0𝑡 (kJ mol^−1)	Δ𝐺^0𝑡/Δ𝐺^0(%)
0.01	−27.41	−11.27	−16.14	58.88
0.02	−25.59	−9.57	−16.02	62.59
0.05	−25.15	−7.33	−17.82	70.85
0.10	−21.05	−5.64	−15.42	73.23