Journal of Spectroscopy / 2013 / Article / Tab 3

Research Article

The Spectrophotometric Multicomponent Analysis of a Ternary Mixture of Paracetamol, Aspirin, and Caffeine by the Double Divisor-Ratio Spectra Derivative Method

Table 3

Determination of paracetamol, aspirin, and caffeine in Excedrin tablets by the proposed method.

Sample*Added (mg)Found (mg)Recovery (%)
PARASPCAFPARASPCAFPARASPCAF

Brand I325.7866.50331.51100.24102.30102.00
88.5065.0065.13408.99128.70322.70106.0095.6094.00

Brand II329.4866.95328.93101.37103.00101.20
237.22195.00196.57574.08273.65531.40103.11106.00103.00

Average102.68101.72100.05
RSD (%)2.444.314.10

1 and 2 are Excedrin tablets containing paracetamol (325 mg), aspirin (325 mg), and caffeine (65 mg) in each tablet from Bristol-Meys Squibb and Novartis Consumer Health companies for brands 1 and 2, respectively.

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.