Kinetic Spectrophotometric Determination of Gemifloxacin Mesylate and Moxifloxacin Hydrochloride in Pharmaceutical Preparations Using 4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole

Table 1

Comparison between the reported spectrophotometric methods for determination of GMF.

Reagent	𝜆max nm	Concentration range; (𝜇g mL^−1)	Molar absorptivity; L mol^−1 cm^−1	Reference
UV spectrophotometry	272	8–40		[17]
UV spectrophotometry	267	10–70		[19]
Iodine	290	6.0–30	1.46×10^4	[23]
2, 3-Dichloro-5, 6-dicyano-p-benzoquinone (DDQ)	470	2.0–10	4.17×10^4
7,7,8,8-Tetracyanoquinodimethane (TCNQ)	840	2.5–12.5	3.42×10^4
Tetracyanoethylene (TCNE)	420	1.0–5.0	8.41×10^4
Safranin O	525	3.0–15	2.81×10^4	[24]
Methylene blue	650	4.0–20	2.20×10^4
Naphthol blue 12BR	620	2.0–10	4.02×10^4
Azocarmine G	540	2.0–10	4.15×10^4
Folin-Ciocalteu/NaOH	685	10–50		[25]
3-Methyl-2-benzothiazolinone hydrazone FeCl3	617	10–100
FeCl3/1,10-phenanthroline	466	40–200
Ninhydrine (DMF)	590	4.0–32	9.68×10^3	[26]
Ascorbic acid (DMF)	530	8.0–40	5.58×10^3
p-benzoquinone (PBQ)	400	9.0–72	4.98×10^3
Palladium/zero order	430	2.0–14	1.365×10^4	[28]
Palladium/1st derivative	480	1.0–10	9.37×10^4
Palladium/2nd derivative	500	1.0–15	1.59×10^4
NBD-Cl	466	0.5–8.0	4.0892×10^4	Present work