Use of Novel Polyurethane Microspheres in a Curcumin Delivery System

Table 3

Pharmacokinetic parameters of different curcumin formulations.

Formulation	𝐶max (ng/mL)	𝑇max (h)	AUC0→∞ (ng/mL h)	𝑇1/2 (h)
Curcumin	194.02 ± 14.75	0.5 ± 0.12	348.77 ± 44.83	0.91 ± 0.28
Cur-PUMs	803.27 ± 50.81	3.0 ± 0.23	3873.95 ± 265.22	5.61 ± 0.53

Values are reported as mean ± S.E.M. (𝑛=5). 𝐶_max: maximum concentration; 𝑇_max: time to reach peak concentration; AUC: area under the plasma concentration-time curve from 0 h to ∞; 𝑇_1/2: half-life.