Fourier Transform Infrared Spectroscopic Imaging of Fracture Healing in the Normal Mouse

Figure 1

Different histological areas within the fracture callus that were studied by FTIRI. Normal cortical bone (CO) remote of the callus served as reference bone. Scale bars = 100 μm. (CC) areas of calcified cartilage; (EC) = areas of endochondral new bone formation; (WB) areas of woven bone formation; (IM) = areas of intramembranous new bone formation. Correlation of TMD and mineral/matrix ratio in the fracture callus is in Figure 2(c). The mineral/matrix values for each area of the callus were plotted versus the time at which a given TMD was measured. The least square best line shown was fitted through all these data points.