Longitudinal Raman Spectroscopic Observation of Skin Biochemical Changes due to Chemotherapeutic Treatment for Breast Cancer in Small Animal Model

Figure 6

Variations of Raman spectra from rat group with regard to the baseline (baseline means the day high-dose chemotherapy was started). The spectrum for each day was subtracted from the baseline signal. Positive values mean that the intensity was decreased, and the negative values mean that the intensity was increased with respect to the baseline signal. Day means day postchemotherapy.

(a)

(b)

(c)

(d)