4-Hydroxycoumarin Derivative: N-(diphenylmethyl)-2-[(2-oxo-2H-chromen-4-yl)oxy]acetamide Interaction with Human Serum Albumin

Table 1

Fluorescence binding parameters for HSA-coumarin derivatives (pH 7.4).

Compound	T (K)	kq (×10^13 l · mol^−1·s^−1)	Kb (×10^5 l/mol)		ΔH° (kJ/mol)	ΔG° (kJ/mol)	ΔS° (J/mol/K)
Coumarin derivatives	293	7.41	6.04	1.15		−25.34
	298	5.82	5.67	1.11	−10.35	−25.76	86.51
	303	4.38	5.48	1.10		−26.19