Automation of the Peak Fitting Method in Bone FTIR Microspectroscopy Spectrum Analysis: Human and Mice Bone Study

Figure 8

The Bland–Altman plot of the human bone spectra (manual method-automatic method values). The straight line is the mean of the differences. The dashed line is the mean of the differences plus or minus 1.96 ∗ SD, representing the limit of agreement. 92% of Crystallinity Index values, 93% of Mineral Maturity values, and 92% of Collagen Maturity values are within the dashed lines. Shifts of 0.0007 cm for the Crystallinity Index, 0.11 for the Mineral Maturity, and 0.17 for the Collagen Maturity are observed.

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