Automation of the Peak Fitting Method in Bone FTIR Microspectroscopy Spectrum Analysis: Human and Mice Bone Study

Figure 9

The Bland–Altman plot of the mice bone spectra (manual method-automatic method values). The straight line is the mean of the differences. The dashed line is the mean of the differences plus or minus 1.96 ∗ SD, representing the limit of agreement. 90% of Crystallinity Index values, 100% of Mineral Maturity values, and 100% of Collagen Maturity values are within the dashed lines. Shifts of −0.0009 cm for the Crystallinity Index, −0.01 for the Mineral Maturity, and 0.21 for the Collagen Maturity are observed.

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