The In Vivo Evaluation on Total Components from Extract of Aconitum Based on a New Analytic Method of Area under Absorbance-Wavelength Curve

Table 4

The mean values of AUAWC and concentrations of total components ().

Dose	Time (h)	Mean AUAWC values of plasma	AUAWC values of drug	Concentration (µg/ml)
Single dose	0.00	45.00	0.00	0.00
	0.25	45.98	0.98	0.00
	0.50	53.71	8.71	4.38
	1.00	57.66	12.66	7.58
	2.00	58.44	13.44	8.21
	4.00	57.71	12.71	7.62
	6.00	54.34	9.34	4.89
	8.00	52.79	7.79	3.64
	12.00	49.13	4.13	0.68
Multiple dose	−48.00	47.18	3.69	0.32
	−24.00	48.55	3.84	0.44
	0.00	44.68	0.00	0.00
	0.25	48.81	4.13	0.68
	0.50	52.76	8.08	3.87
	1.00	51.81	7.13	3.11
	2.00	54.66	9.98	5.41
	4.00	52.73	8.05	3.85
	6.00	50.14	5.46	1.75
	8.00	49.92	5.24	1.58
	12.00	47.24	2.56	0.00