Change in the Microviscosity of Erythrocyte Membranes and Proteins in Blood Plasma after Graphene Oxide Addition: The ESR Spectroscopy Study

Table 1

Parameters of ESR spectra (probe correlation time () and isotropic splitting constant ()) of spin probes 1 and 2 in the erythrocyte membranes and blood plasma.

Sample	Probe		τ^+1 · 10^9 (sec)	τ^− 1 · 10^9 (sec)	τ^±1 · 10^9 (sec)
Erythrocytes (control)	2	15.4	3.19 ± 0.27	1.37 ± 0.12	6.2 ± 0.49
Erythrocytes + GO	2	15.4	3.07 ± 0.26	1.5 ± 0.12	6.08 ± 0.48
Erythrocytes + GO, 1 hour of incubation	2	15.4	3.45 ± 0.30	1.72 ± 0.14	6.3 ± 0.5
Erythrocytes + GO, 4 hours of incubation	2	15.4	3.40 ± 0.3	1.69 ± 0.14	6.38 ± 0.5
Blood plasma (control)	1	11.7	1.13 ± 0.08	0.65 ± 0.05	1.52 ± 0.12
Blood plasma + GO, 1 hour of incubation	1	11.6	1.1 ± 0.08	0.64 ± 0.05	1.50 ± 0.12
Blood plasma + GO, 4 hours of incubation	1	12.8	1.23 ± 0.09	0.75 ± 0.06	1.73 ± 0.13
Blood plasma + GO, 20 hours of incubation	1	13.9	1.47 ± 0.11	0.86 ± 0.07	2.14 ± 0.17
Blood plasma (control)	2	16.8	1.74 ± 0.13	1.12 ± 0.09	2.92 ± 0.23
Blood plasma + GO, 1 hour of incubation	2	16.7	1.68 ± 0.12	1.08 ± 0.085	2.84 ± 0.2
Blood plasma + GO, 4 hours of incubation	2	16.8	1.64 ± 0.12	1.04 ± 0.08	2.79 ± 0.2
Blood plasma + GO, 20 hours of incubation	2	17.2	1.53 ± 0.1	1.04 ± 0.08	2.34 ± 0.18