Chemometrics-Enabled Raman Spectrometric Qualitative Determination and Assessment of Biochemical Alterations during Early Prostate Cancer Proliferation in Model Tissue

Table 1

Raman band assignments of PC3 and PNT1a prostatic cells.

Raman shift (cm^−1)	Functional groups and molecular vibration assignments	References
519	Phosphatidylinositol	[9]
615	Cholesterol esters	[9]
638	C-C stretch, C-C twisting of tyrosine proteins	[9, 16]
700, 702	Cholesterol esters	[9]
852, 857	Ring-breathing modes (tyrosine proteins)	[16]
889	Structural protein modes of tumors	[9]
921	C-C stretch (proline ring, glucose, and lactic acid)	[9]
927	Proteins	[9]
1001	Proteins (phenylalanine)	[9, 13]
1084	Phosphodiester groups in nucleic acids	[9]
1126	Protein, phospholipids	[13]
1256, 1261	C-N stretch (proteins), CH2 twisting and wagging (lipids and proteins), C-H bend (phospholipids)	[29]
1445	CH2 bending (proteins)	[16]
1450	DNA/RNA, proteins, lipids	[13, 16]
1552, 1554	υ(C=C) stretching modes (tryptophan), amide II	[9]
1582	C=C bending mode of phenylalanine (proteins)	[16]
1602	C=C bending modes (phenylalanine and tyrosine proteins)	[16]
1657	C=O stretch (proteins and lipids), C=C stretch (lipids), nucleic acids	[9, 29]