Chemometrics-Enabled Raman Spectrometric Qualitative Determination and Assessment of Biochemical Alterations during Early Prostate Cancer Proliferation in Model Tissue

Table 2

Comparison of peak intensity ratios between malignant (PC3) and normal cells (PNT1a) at 566 ± 0.70 cm⁻¹, 630 cm⁻¹, 1370 ± 0.86 cm⁻¹, and 1618 ± 1.73 cm⁻¹ spectral regions.

Raman shift (cm^−1)	Raman intensities (arbitrary units)
	Stage 1		Stage 2		Stage 3		Band ratios
	PNT1a	PC3	PNT1a	PC3	PNT1a	PC3	PC3(1)/PNT1a(1)	PC3(2)/PNT1a(2)	PC3(3)/PNT1a(3)
565	0.90	0.87	0.75	0.85	0.75	0.87	0.967	1.133	1.16
568	0.81	0.87	0.77	0.86	0.77	0.89	1.074	1.117	1.156
630	0.69	0.79	0.73	0.86	0.62	0.85	1.145	1.178	1.371
1368	0.51	0.47	0.72	0.66	0.68	0.58	0.922	0.917	0.853
1372	0.40	0.44	0.71	0.65	0.60	0.53	1.1	0.915	0.883
1617	0.32	0.35	0.46	0.43	0.58	0.53	1.094	0.935	0.914
1621	0.30	0.32	0.59	0.54	0.49	0.44	1.067	0.915	0.898