Research Article

Chemometrics-Enabled Raman Spectrometric Qualitative Determination and Assessment of Biochemical Alterations during Early Prostate Cancer Proliferation in Model Tissue

Table 6

Comparison of band intensity ratios between malignant (PC3) and normal cells (PNT1a) based on the weak Raman bands at 1076 cm−1 and 1232 cm−1.

Raman shift (cm−1)Raman intensities (arbitrary units)
Stage 1Stage 2Stage 3Band ratios
PNT1aPC3PNT1aPC3PNT1aPC3PC3(1)/PNT1a(1)PC3(2)/PNT1a(2)PC3(3)/PNT1a(3)

10760.670.650.640.640.740.770.9701.01.04
12320.600.550.740.680.790.780.9170.9190.987

The numbers 1, 2, and 3 enclosed in brackets identify the stage of cell proliferation.