Research Article
Investigation on the Binding and Conformational Change of All-trans-Retinoic Acid with Peptidyl Prolyl cis/trans Isomerase Pin1 Using Spectroscopic and Computational Techniques
Figure 2
Fluorescence spectra of Pin1-ATRA complex. (a, b) Fluorescence emission spectra of Pin1 in the absence and presence of ATRA at 293 K and 303 K, respectively. λex = 295 nm, cpin1 = 5 μM, and cATRA = 0 (red line), 0.5 (blue line), 1 (magenta line), 2 (olive line), 3 (navy line), 4 (violet line), and 5 (purple line) μM. (c) Stern–Volmer and (d) double logarithmic plot for the interaction of Pin1 and ATRA.
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