Research Article

GC-MS Phytochemical Profiling, Antidiabetic, and Antioxidant Activities of Khaya senegalensis Stem Bark and Azadirachta indica Leaves Extracts in Rats

Table 4

Influence of oral administration of K. senegalensis stem bark and A. indica leaf hydroethanolic extracts on kidney function markers in diabetic rats.

Animal groupsUrea (mg/dl)Creatinine (mg/dl)

Normal control (A)34.10 ± 5.400.63 ± 0.05
Diabetic control (B)83.67 ± 3.661.23 ± 0.26
Glibenclamide (C)28.20 ± 3.030.69 ± 0.04
K. senegalensis extract (F)44.64 ± 12.480.66 ± 0.04
A. indica extract (H)54.37 ± 8.530.77 ± 0.03

Statistically significant difference at , in comparison to diabetic control (group B). Values presented as mean ± SE; treatment period: 28 days.