GC-MS Phytochemical Profiling, Antidiabetic, and Antioxidant Activities of Khaya senegalensis Stem Bark and Azadirachta indica Leaves Extracts in Rats

Table 6

Phytochemical compounds identified in K. senegalensis stem bark and A. indica leaf extracts by GC-MS analyses.

RT	Name of the compounds	Molecular formula	Molecular weight	% abundancein K. Senegalensis	% abundancein A. Indica	Structures and biological significance
13.75	Methoxy-phenyl-oxime	C8H9NO2	151	—	0.82	Antioxidant, antimicrobial [42]
30.02	4H-Pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl	C6H8O4	144	—	1.42	Antioxidant [43]
48.50	Elemene	C15H24	204	—	0.43	Antioxidant, antibacterial [44]
71.40	n-Hexadecanoic acid	C16H32O2	256	0.76	3.77	Antioxidant, hypocholesterolemic, 5-alphareductase activity [45, 46]
75.43	Phytol	C20H40O	296	—	7.40	Antioxidant, antidiabetic, antimicrobial, anticancer, anti-inflammatory activities [45, 47]
76.89	9,12,15-Octadecatrienoic acid, (Z,Z,Z)-	C18H30O2	278	—	3.28	Antidiabetic, antidiabetic, anticancer, antimicrobial, antiatherosclerotic activities [45]
77.62	Ethyl 9,12,15-octadecatrienoate	C20H34O2	306	—	1.42	Antioxidant, antiatherosclerotic, antidiabetic, antihypertensive, anticancer, hepatoprotective, antiarthritic activities [45, 48]
90.47	Hexadecanoic acid, 2-hydroxy-1-(hydroxymethyl) ethyl	C19H38O4	330	—	1.41	Antioxidant, 17-beta-hydroxysteroid dehydrogenase inhibitor, arachidonic acid inhibitor, testosterone hydroxylase inhibitor, uric acid production inhibitor [45, 49]
114.23	β-Sitosterol	C29H50O	414	—	0.69	Antioxidant, antidiabetic activities [47]

% abundance represented the area percentage observed in the GC-MS chromatograms.