Research Article

Clinical, Biochemical, and ATR-FTIR Spectroscopic Parameters Associated with Death or Survival in Patients with Severe COVID-19

Table 4

Biochemical parameters on hospitalized patients with severe COVID-19.

COVID-19 Media (IQR)Survival Media (IQR)Death Media (IQR)

Blood chemistry test
 Creatinine (mg/dL)0.7 (0.6, 0.8)0.7 (0.5, 0.8)0.8 (0.7, 1.2)0.005
 Urea (mg/dL)38.5 (30, 50.3)36.4 (27.8, 47.1)66.3 (55.6, 96.3)0.0001
 Glucose (mg/dL)121 (91.5, 165.5)119 (87, 161)154 (131, 178)0.081
Serum electrolytes
 Na (mmol/L)137 (135, 139)137 (135, 139)138 (136, 139)0.943
 K (mmol/L)4.3 (3.9, 4.6)4.2 (3.9, 4.6)4.8 (4.3, 5.1)0.093
Hepatic-function test
 ALT (U/L)43 (29, 72)49.5 (31, 75)29 (20, 43)0.01
 AST (U/L)34 (25, 43.5)34 (25, 44)30 (23, 41)0.599
 ALP (U/L)87 (72, 122.5)88 (69, 123)85 (76, 121)0.652
 Albumin (g/dL)3 (2.7, 3.3)3.1 (2.8, 3.4)2.7 (2.6, 3.0)0.004
Inflammatory markers
 CRP (mg/dL)22.6 (8.7, 126.5)18.9 (7.0, 70.3)131.3 (57.1, 169.0)0.0001
 LDH (UI/L)269 (222.5, 350)131 (57, 169)380 (305, 602)0.0001
 Fibrinogen (mg/dL)461 (364, 701.5)444 (477, 476)611 (477, 746)0.099

The bold values refer to statistical significance in each group.