Expression of Concern on “A Novel Interaction between Pyk2 and MAP4K4 Is Integrated with Glioma Cell Migration”
Journal of Signal Transduction would like to express concern with the article titled “A Novel Interaction between Pyk2 and MAP4K4 Is Integrated with Glioma Cell Migration”  due to concerns regarding the biological origin of the cell line SF767 used.
Cell line SF767 has been reported to show a DNA fingerprint identical to the cervical cancer cell line ME-180 , and hence its suitability as an appropriate model for glioma is in question. The authors did not respond to our requests for clarification and the editorial board therefore wish to make readers aware of the limitations to the interpretation of results in the context of gliomas.
P. Bady, A.-C. Diserens, V. Castella et al., “DNA fingerprinting of glioma cell lines and considerations on similarity measurements,” Neuro-Oncology, vol. 14, no. 6, pp. 701–711, 2012.View at: Google Scholar