Research Article

Developmental and Reproductive Effects of SE5-OH: An Equol-Rich Soy-Based Ingredient

Table 1

Isoflavone constituents of SE5-OH.

Isoflavone i n g r e d i e n t Reproductive toxicity study ( L o t 0 6 0 1 0 6 P ) (mg/g)Reproductive toxicity study and developmental toxicity study ( L o t 0 5 1 2 0 6 P ) ( m g / g )

Daidzein 0 . 3 2 3 ± 0 . 0 0 1 5 0 . 2 7 5 ± 0 . 0 0 2 5
Genistein 0 . 2 9 3 ± 0 . 0 0 1 7 0 . 2 8 7 ± 0 . 0 0 3 2
Glycitein 1 . 6 5 ± 0 . 0 1 5 2 . 0 4 ± 0 . 0 1 0
Dihydrodaidzein 0 . 3 6 2 ± 0 . 0 0 2 1 0 . 3 3 7 ± 0 . 0 0 3 6
Equol 5 . 1 6 ± 0 . 0 7 0 5 . 2 4 ± 0 . 0 2 5

T h e amount of each isoflavone ingredient is the average of three separate measurements, mean ± standard deviation. B o t h lots were used in the reproductive study, while only Lot 051206P was used in the developmental study.