Developmental and Reproductive Effects of SE5-OH: An Equol-Rich Soy-Based Ingredient

Table 7

Effects of SE5-OH administration on F₀ generation rat dam gestation and delivery parameters.

Dose (mg/kg/day)		Gestation length (days)	Number of implantation sites	Number of offspring born alive	Birth index^A (%)	Gestation index^B (%)
0		22.3±0.5	15.0±3.9	13.8±4.1	87.12±21.64	96
	𝑛	24	25	25	25
200		22.2±0.4	15.1±3.6	13.8±3.4	89.03±20.48	95.8
	𝑛	23	24	24	24
1000		22.3±0.6	15.3±1.7	13.6±3.3	89.27±19.68	100.0
	𝑛	22	22	22	22
2000		22.0±0.3	14.7±2.1	13.8±2.3	93.63±9.28	100.0
	𝑛	22	22	22	22

Significantly different from control: ^∗𝑃<.05, ^∗∗𝑃<.01; ^Abirth index = (number of offspring born alive divided by the number of implantations); ^Bgestation index = (number of females with live offspring divided by the number of pregnant females); 𝑛: number of dams per group.