Developmental and Reproductive Effects of SE5-OH: An Equol-Rich Soy-Based Ingredient

Table 9

Sperm parameters in control and high-dose male rats used as breeding males in the F₀ and F₁ two-generation reproduction study.

Dose (mg/kg/day)	Sperm motility (%)	HRS (×10^6/g)	Sperm count (cauda epididymal) (×10^6/g)	Abnormal sperm (%)	Types of abnormal sperm (%) no.					Tailless sperm (%)
					A	B	C	D	E
F0 generation
0	91.0±4.5	83.73±12.52	534.73±72.79	0.81±1.26	0.25±0.62	0.04±0.14	0.00±0.00	0.42±0.76	0.10±0.40	1.96±2.03
𝑛	26	26	26	26	26	26	26	26	26	26
2000	91.3±3.2	83.64±10.21	537.29±66.92	0.33±0.37	0.04±0.14	0.00±0.00	0.00±0.00	0.29±0.35	0.00±0.00	1.81±2.83
𝑛	26	26	26	26	26	26	26	26	26	26
F1 generation
0	86.0±20.1	75.98±17.86	551.21±151.94	0.52±0.83	0.31±0.43	0.00±0.00	0.00±0.00	0.21±0.62	0.00±0.00	1.95±1.77
𝑛	22	22	22	21	21	21	21	21	21	21
2000	86.7±19.7	81.57±14.31	557.51±142.72	0.40±0.71	0.19±0.51	0.00±0.00	0.00±0.00	0.21±0.34	0.00±0.00	5.18±15.30
𝑛	22	22	22	22	22	22	22	22	22	22

A: without hook, B: banana-like head, C: amorphous, D: folded in midpiece, E: others; HRS: homogenization-resistant spermatids; 𝑛: number of males per group.