Clastogenic Effects of Glyphosate in Bone Marrow Cells of Swiss Albino Mice

Table 1

Effect of glyphosate treatment on induction of chromosomal aberration in swiss albino mice.

		Groups	Untreated	B(a)P	Glyphosate	Glyphosate
				(100 mg/kg b.wt)	(25 mg/kg b.wt)	(50 mg/kg b.wt)
		Breaks	0.36 ± 0.1	5.65 ± 0.4	2.86 ± 0.2	3.79 ± 0.16
		Fragments	0.17 ± 0.01	1.59 ± 0.03	0.39 ± 0.1	1.94 ± 0.02
	24 hours	Exchange	0.26 ± 0.02	0.69 ± 0.2	0.47 ± 0.3	0.41 ± 0.01
	of treatment	Multiple damage	1.02 ± 0.07	4.83 ± 0.3	2.14 ± 0.4	1.32 ± 0.07
		Total no. of	1.81±0.03	12.76±0.17*	5.86 ± 0.12*	7.46±0.14*
		aberrant cells
Number of		Breaks	0.33 ± 0.2	6.84 ± 0.5	3.37 ± 0.05	4.51 ± 0.07
aberrant cells		Fragments	0.19 ± 0.01	2.63 ± 0.7	0.46 ± 0.03	0.89 ± 0.01
(%) after	48 hours	Exchange	0.23 ± 0.1	0.83 ± 0.03	0.59 ± 0.01	0.54 ± 0.02
	of treatment	Multiple damage	1.17 ± 0.04	4.05 ± 0.04	2.82 ± 0.06	2.91 ± 0.16
		Total no. of	1.92±0.03	14.35±1.27*	7.24±0.15*	8.85±0.14*
		aberrant cells
		Breaks	0.34 ± 0.02	6.91 ± 0.10	4.42 ± 0.07	4.49 ± 0.13
		Fragments	0.15 ± 0.01	2.93 ± 0.04	0.53 ± 0.02	0.82 ± 0.02
	72 hours	Exchange	0.19 ± 0.01	1.65 ± 0.06	0.47 ± 0.03	0.63 ± 0.02
	of treatment	Multiple damage	1.12 ± 0.04	3.73 ± 0.1	2.34 ± 0.09	3.30 ± 0.15
		Total no. of	1.80±.05	15.22* ± 1.19	7.76 ± 0.4*	9.24±0.18*
		aberrant cells

Mean ± SE of animals n = 5.
^∗𝑃<.05.