Molecular and Biochemical Effects of a Kola Nut Extract on Androgen Receptor-Mediated Pathways
Figure 5
Modulation of prostate cell proliferation by Bizzy
nut extracts. LNCaP or DU145 cells were grown in the presence of 0–1000 ppm Biz-2
for 24 hours, and cell growth was determined using (a)
3[H] thymidine incorporation, (b) MTT cell viability assay and tryphan
blue dye staining, and (c) cytotoxicity
of Biz-2 in LNCaP cells that was performed as described in Section 2. Growth inhibitory
activity of the extracts was determined as . Each value represents mean ± SEM for three experiments performed in
eight wells of a 96-well plate. Values followed by differed
significantly from the controls.
