Journal of Toxicology / 2009 / Article / Tab 3

Research Article

Cytotoxic Effect of the Genus Sinularia Extracts on Human SCC25 and HaCaT Cells

Table 3

The changes of cell cycle distribution of the genus Sinularia extracts in SCC25 and HaCaT cells.

Cell linesNo.Treatment (μg/mL)Sub-G1 phaseG0/G1 phaseS phaseG2/M phase
Mean%Mean%Mean%Mean%

SCC25Control01.0100.052.3100.019.8100.027.2100.0
1IC5032.53250.037.772.116.583.313.850.7
IC8064.16410.021.941.97.336.96.825.0
2IC5018.71870.046.889.415.779.319.872.8
IC8058.95890.024.146.18.341.98.832.4
3IC5023.62360.054.3103.812.261.610.538.6
IC8069.86980.018.635.66.834.44.817.6
4IC5033.43340.037.772.114.472.714.854.4
IC8080.18010.013.425.63.618.23.111.4
5IC5024.32430.051.197.712.563.112.546.0
IC8036.83680.040.477.212.864.610.337.9
6IC5033.73370.032.862.715.578.318.367.3
IC8079.67960.012.423.74.422.23.613.2

HaCaTControl00.8100.059.5100.016.210023.7100.0
1IC5035.34412.534.357.613.180.916.770.5
IC8069.48675.06.711.37.948.816.167.9
2IC5019.42425.042.871.917.8109.920.385.7
IC8052.36537.515.325.715.193.217.473.4
3IC5025.13137.545.276.016.4101.213.958.6
IC8056.17012.513.222.216.110015.163.7
4IC5039.14887.538.264.213.180.99.640.5
IC8071.38912.58.113.69.961.110.946.0
5IC5035.84475.035.459.515.495.113.858.2
IC8058.97362.511.920.014.388.315.163.7
6IC5057.47175.010.217.112.879.019.783.1
IC8072.99112.55.59.28.351.213.356.1

(i) S. grandilobata, 1; S. parva, 2; S. triangula, 3; S. scabra, 4; S. nanolobata, 5; S. gibberosa, 6.

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