Effects of Cytochrome P450 Inhibitors on Itraconazole and Fluconazole Induced Cytotoxicity in Hepatocytes

<table class="table-group" width="800px"><tr class="fig-image" id="a"><td><img alt="912320.fig.002a" src="https://static.hindawi.com/articles/jt/volume-2009/912320/figures/912320.fig.002a.jpg"/></td></tr><tr class="fig-caption"><td align="center"><table><tr><td><b>(a) </b>Curcumin</td></tr></table></td></tr><tr class="fig-image" id="b"><td><img alt="912320.fig.002b" src="https://static.hindawi.com/articles/jt/volume-2009/912320/figures/912320.fig.002b.jpg"/></td></tr><tr class="fig-caption"><td align="center"><table><tr><td><b>(b) </b>SKF 525A</td></tr></table></td></tr></table>

<table>Effects of Cytochrome P450 inhibitors on the percentage viability of hepatocytes. *Significant different (<svg height="11.375" id="M8" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 50.549999 11.375" width="50.549999" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>) when compared to controls. Values are mean <svg height="9.5625" id="M9" style="vertical-align:-0.3003pt" version="1.1" viewbox="0 0 10.1 9.5625" width="10.1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> sd of 3 separate experiments.</table>

Journal of Toxicology

fig2

Figure 2

Figure 2: Effects of Cytochrome P450 Inhibitors on Itraconazole and Fluconazole Induced Cytotoxicity in Hepatocytes 