Research Article

In Vitro Study of Mutagenesis Induced by Crocidolite-Exposed Alveolar Macrophages NR8383 in Cocultured Big Blue Rat2 Embryonic Fibroblasts

Table 2

DCF fluorescence in particle-exposed NR8383 analysed by flow cytometry.

TreatmentMean fluorescence ± SD(1)

Control77.1 ± 5,9
Crocidolite 1 μg/cm271.5 ± 2,9
Crocidolite 5 μg/cm265.9 ± 13,5
Crocidolite 10 μg/cm265.7 ± 15,2
Zymosan 10 μg/cm2236.5 ± 19,1*

(1)Result obtained from three experiments.
*Statistically different from control values (P<.05).