The Influence of Bovine Milk High or Low in Isoflavones on Hepatic Gene Expression in Mice

Table 2

Total concentrations (free and conjugated) of the measured phytoestrogens (ng/ml) and endogenous estrogens E1 and E2 (pg/mL) in high (HIM) and low (LIM) isoflavone milk.

	LIM	HIM
Isoflavones
Formononetin${}^{*}$	$10.7\pm 0.2$	$20.4\pm 0.9$
Biochanin A${}^{*}$	$1.3\pm 0.07$	0
Glycitein${}^{*}$	$5.9\pm 0.1$	$10.2\pm 1.0$
Daidzein${}^{*}$	$0.3\pm 0.02$	$5.7\pm 0.05$
Isoflavone metabolite
Equol${}^{*}$	$57.4\pm 0.9$	$1003\pm 37$
Flavone
Chrysin${}^{*}$	0	$0.4\pm 0.02$
Flavanone
Naringenin${}^{*}$	$13.4\pm 0.1$	$16.5\pm 0.7$
Lignans
Matairesinol${}^{*}$	0	$48.5\pm 5.5$
Enterodiol${}^{*}$	$4.0\pm 0.04$	$2.6\pm 0.2$
Enterolactone${}^{*}$	$24.6\pm 0.4$	$11.0\pm 1.3$
Coumestans
Coumestrol	0	0
Total${}^{*}$	118	1215
Estrone (E1)	$566\pm 17$	$503\pm 17$
17$\beta$-estradiol (E2)	$64.6\pm 5$	$60.0\pm 5$

${}^{*}$Statistically significant difference between LIM and HIM.