Toxicological Characterization of the Inorganic and Organic Arsenic Metabolite Thio-DMAV in Cultured Human Lung Cells

Figure 5

DNA strand break formation after 1 h (a) and 24 h (b) incubation with thio-DMA^V in A549 cells. DNA strand breaks were quantified by alkaline unwinding; 5 min incubation with 75 μM H₂O₂ served as positive control. Shown are mean values of at least six determinations + SD.

(a)

(b)