Cytotoxicity of Environmentally Relevant Concentrations of Aluminum in Murine Thymocytes and Lymphocytes
Figure 2
Dose and time dependence of AlCl3-induced injury in thymocytes. The cells were treated with a range of concentrations of AlCl3 (0–40 μM) at various time points. Thymocytes were considered to be damaged when the level of fluorescence intensity of PI in the cells was higher than the level in untreated cells. Values are mean ± SD obtained from six independent measurements (based on Student’s paired -test). The concentration curves are all statistically significantly different at the level by ANOVA analysis. There are no significant changes with time between 25, 40, and 60 minutes, nor between 10 and 15 minutes, but all other time differences are significant.
