Application of Purified Botulinum Type A Neurotoxin to Treat Experimental Trigeminal Neuropathy in Rats and Patients with Urinary Incontinence and Prostatic Hyperplasia

<table>Simple procedure for purifying type A and B NTXs. Partially purified type A HA-positive PTXs (L and LL) or trypsin-treated (fully activated) type B L toxin was layered on a lactose gel column under acidic conditions (pH 6.0). After washing, the pH was adjusted to 8.0 to obtain the NTX. The bound HA-positive PTX(s) and nontoxic components were eluted with buffer supplemented with 0.2 M lactose.</table>

Journal of Toxicology

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Figure 2: Application of Purified Botulinum Type A Neurotoxin to Treat Experimental Trigeminal Neuropathy in Rats and Patients with Urinary Incontinence and Prostatic Hyperplasia 

Figure 2 | Application of Purified Botulinum Type A Neurotoxin to Treat Experimental Trigeminal Neuropathy in Rats and Patients with Urinary Incontinence and Prostatic Hyperplasia 