Research Article

Bayesian Analysis of a Lipid-Based Physiologically Based Toxicokinetic Model for a Mixture of PCBs in Rats

Table 3

Basal CYP1A/2B parameters [17].

ParameterSymbolUnitsValue

Initial steady-state CYP1A/2B 𝐴 0 nmol/g protein0.1
CYP1A/2B degradation 𝑘 𝑒 h−10.04
Basal CYP1A/2B production 𝑘 0 nmol/h/g protein0.004

Computed from the steady-state mass balance.